Festival dijadwalkan dari 19 Mei hingga 21 Mei 2016 (2 hari).
The Great Escape berlangsung di Brighton, United Kingdom. Berikut adalah alamat lengkap festival: Brighton and Hove, England
Larkin Poe, Idles, Jacob Collier, Stormzy, Craig David, RY X, Tom Misch, Declan Mckenna, Khruangbin, Michael Kiwanuka, Blossoms, Barns Courtney, Alice Phoebe Lou, Loyle Carner, Jake Bugg, Fatoumata Diawara, Mahalia, Fakear, The Hunna, Jain, The Rubens, Gang of Youths, Oh Wonder, Anne‐Marie, Banners, Tom Walker, Julia Jacklin, Hyphen Hyphen, YOnaka, Highasakite, Margo Price, Muna, Tim Vantol, The Temper Trap, Mabel, Mura Masa, The Joy Formidable, The Amazons, The Sherlocks, Night Beats.
Genre dan sub-genre yang paling populer dari edisi sebelumnya adalah:
rock
electronic
pop
indie
indie rock
indie pop
alternative
alternative rock
experimental
electronica
dream pop
indie folk
acoustic
post-punk
chillout
dance
psychedelic
rnb
ambient