Festival dijadwalkan dari 25 Agu hingga 27 Agu 2006 (2 hari).
Reading Festival berlangsung di Reading, United Kingdom. Berikut adalah alamat lengkap festival: RG1 8EQ Reading
Arctic Monkeys, Muse, My Chemical Romance, Fall Out Boy, Placebo, Pearl Jam, Rise Against, Panic! at the Disco, Bullet for My Valentine, Coheed and Cambria, The Kooks, Flogging Molly, Killswitch Engage, Taking Back Sunday, Franz Ferdinand.
Genre dan sub-genre yang paling populer dari edisi sebelumnya adalah:
rock
punk
pop
alternative
indie
indie rock
alternative rock
indie pop
britpop
post-punk
punk rock
emo
hardcore
experimental
garage rock
post-hardcore
screamo
electronica
metal