Festival dijadwalkan dari 28 Jul hingga 31 Jul 2016 (3 hari).
Lollapalooza Chicago berlangsung di Chicago, United States. Berikut adalah alamat lengkap festival: GRANT PARK – CHICAGO, IL
Lana Del Rey, Red Hot Chili Peppers, Dua Lipa, Chris Stapleton, Melanie Martinez, Ghost, The 1975, Halsey, Bastille, Martin Garrix, Lindsey Stirling, Marshmello, Third Eye Blind, Nothing but Thieves, Bryson Tiller, Foals, Frank Turner, Aurora, Kehlani, Louis The Child.
Genre dan sub-genre yang paling populer dari edisi sebelumnya adalah:
electronic
rock
hip hop
indie rock
indie
electronica
indie pop
alternative
alternative rock
electropop
dance
electro
house
rnb
synth-pop
trap
dubstep
experimental
dream pop